Friday, April 9, 2021

Sunshine on My Shoulders Makes Me Happy & Lowers Coronavirus Deaths via Nitric Oxide : Lockdowns Kill

 .....As intended.  We're back to the benefits of the good old sun. We've talked the sun and vitamin D. The lack of sun, vitamin D deficiency and the sick season aka respiratory viruses (cold and flu) The plain old energizing benefit of exposure to the sun. In limited quantities it just makes you feel good!  As does being in nature. For this latest we'll have a look at more sun exposure benefit in reducing Coronavirus deaths.

Sunshine linked to lower coronavirus deaths

  • - Scientists from the University of Edinburgh analysed all coronavirus deaths that occurred in mainland US between January and April 2020.
  • - These were compared against the UV levels of more than 2,000 US counties over the same four months.
  • - To adjust for the potential effects of vitamin D, the Edinburgh scientists only looked at counties with insufficient UVB exposure. UVB is "the primary source of vitamin D for the body".
  • - In the UK, the NHS recommends "everyone consider taking a daily supplement containing 10 micrograms of vitamin D during the autumn and winter".
  • - The Edinburgh scientists estimated the US counties' UV rays via satellite data.
  • - The results, published in the British Journal of Dermatology, suggest coronavirus deaths in the US fell by 29% for every 100 kilojoules (KJ) per metre squared increase in daily UVA. KJ is a measure of energy.

Repeated experiments in England and Italy, at different latitudes to the US, produced similar results.

"These early results open up sunlight exposure as one way of potentially reducing the risk of death."

  • UVA may cause the release of nitric oxide, which has been shown to reduce the coronavirus' replication in laboratory studies.

When pooling the English and Italian findings, the fatality decline was estimated at 32%.

  • Results suggest people who live in areas with the highest UVA exposure – a ray behind 95% of the sun's ultraviolet light – are less likely to die with the coronavirus than residents of less sunny counties.
  • The Edinburgh scientists took into account factors that are known to be linked with increased coronavirus exposure and death, like age, ethnicity, socioeconomic status and infection levels in the local area.
  • UVA is said to release nitric oxide from "stores" in the skin, "whence it is mobilised to the systemic circulation", causing blood vessels to dilate and blood pressure to drop, wrote the team.

They stressed the US study was observational, and therefore does not show cause and effect.

Nevertheless, co-author Professor Chris Dibben added: "The relationship between COVID-19 mortality, season and latitude has been quite striking, here we offer an alternative explanation for this phenomenon."

  • The scientists concluded: "If the relationship identified proves to be causal, it suggests optimising sun exposure may be a possible public health intervention. 
  • "Given the effect appears independent of a vitamin D pathway, it suggests possible new COVID-19 therapies and the importance of exploring the role of circulating NO [nitric oxide]."

But what about Brazil?

Some have pointed out, however, coronavirus cases have also spiked in tropical regions. Brazil is the world's second worst affected country, with more than 13 million confirmed cases since the outbreak was identified and over 340,000 deaths.

Skin pigmentation via melatonin can "block UV penetration", wrote the scientists.

Which means an individual might have to spend a bit more time in the sun. Or supplement with Nitric Oxide via supplements, nasal sprays etc. In a safe manner, not to excess.

What is the role of nitric oxide in the body?

Some of the known functions of nitric oxide are listed in the table below.

Cardiovascular system
  • Controls vascular tone.
  • Relaxes vascular smooth muscles and reduces blood pressure.
  • Dilates vessels and relieves the pain of angina.
  • Inhibits the aggregation of platelets within the vessels and prevents thrombotic events.
Nervous system
  • Acts as a neurotransmitter, including in the autonomic nervous system.
  • Increases cerebral blood flow and oxygenation to the brain.
  • One of the important mediators in penile erection during sexual arousal.
Lungs
  • Dilates pulmonary vessels.
  • Beneficial in Adult Respiratory Distress Syndrome, Pulmonary hypertension and Chronic Obstructive Airway Disease.
  • Produced in abnormal amounts in inflammatory lung conditions.
  • Concentration of NO in exhaled air is a marker of airway inflammation.
Gastrointestinal tract
  • Regulates the relaxation of smooth muscles.
  • Controls peristalsis and the function of sphincters.
Renal system
  • Due to its vasodilatory effect, increases blood flow to the kidney.
  • Increases the glomerular filtration rate and the production of urine.
Immune system
  • Modulates T cell-mediated immune response.

Also interesting..

Nitric oxide shows promise as a COVID-19 and mycobacteria treatment

“Based on our knowledge and experience using nitric oxide to treat other lung infections, we believe it could prevent COVID-19 infections from progressing and ultimately improve outcomes for patients, particularly more vulnerable patients,” says Road, a Vancouver Coastal Health Research Institute (VCHRI) researcher.
Sunlight linked with lower Covid-19 deaths, study suggests

Increased exposure to the sun’s rays — specifically UVA — could act as a simple public health intervention if further research establishes it causes a reduction in mortality rates, experts say.

Researchers from the University of Edinburgh compared all recorded deaths from Covid-19 in the continental US from January to April 2020 with UV levels for 2,474 US counties for the same time period.

The study found that people living in areas with the highest level of exposure to UVA rays — which makes up 95 percent of the sun’s UV light — had a lower risk of dying from Covid-19 compared with those with lower levels. The analysis was repeated in England and Italy with the same results.

 GET OUTSIDE- IT'S THE BEST THING FOR WHAT AILS YOU.

Sunlight killing viruses has been discussed previously here:

Recall the ending of this post?  Doug Ford, Ontario’s Legal Drug Cartel Boss, Puts the Province Under House Arrest

All you have to do is live. I mean choose to live. Stay out of  the fear that makes you irrational and live. Remember: Pandemics are Over When the Public Decides They Are Over

What's your decision?

1 comment:

  1. Admittedly not a big John Denver fan, but, really there was no better song to serve as a reminder of how important it is to us to get outdoors and embrace life.

    There is not one day I don't walk- hike, ride. on my fave trails, parks at the beach- winter, spring, summer or fall

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